Zeneca, widely known by the handle Zeneca_33 on X (formerly Twitter), is a pseudonymous NFT collector, creator, and angel investor who became one of the more recognised voices in the Web3 space during the 2021–2023 NFT cycle. He operates primarily as an independent angel rather than through a named fund, which means AUM figures and formal portfolio disclosures are not public.
His background before crypto is not widely disclosed. He built his audience through consistent writing about NFT culture, collecting strategy, and creator economics. His newsletter, NFTs and Coffee, accumulated a substantial subscriber base and became one of the more-read independent publications in the NFT ecosystem. This gave him deal flow and early access that a conventional angel investor would source through a fund network.
In 2022 he launched 333 Club, a members-only NFT community project. The project was both a creative and an investment vehicle, offering holders access to Zeneca's research, deal flow, and community. It positioned him as creator-investor – a model that became common among high-profile NFT personalities. Public information about specific third-party angel investments beyond his own projects is limited; the five portfolio entries associated with his profile reflect projects where his involvement has been publicly cited, though deal sizes have not been disclosed.
Notable investments
- 333 Club – his own NFT membership project, launched 2022
- Several undisclosed early-stage Web3 projects where his advisory role has been mentioned in project announcements but terms were not made public
Public information about his broader angel portfolio is limited. He has not published a formal portfolio page or made LP-style disclosures typical of institutional investors.
Team
Zeneca operates independently under a pseudonym. His real name has not been publicly disclosed as of available records. There are no publicly named managing partners or co-investors formally affiliated with his angel activity. He has collaborated with other pseudonymous collectors and creators within the NFT community, but these are not structured fund partnerships.
Recent activity
Through 2024 and into 2025, Zeneca shifted focus alongside the broader NFT market contraction. Activity on his newsletter and social channels continued, with commentary moving toward broader crypto market topics in addition to NFTs. No new major fund announcements or large disclosed investments were made public during this period. The NFT market downturn from its 2021–2022 peak affected collector-investors in this cohort significantly, and Zeneca has been candid in public posts about the difficulty of the market environment.
Geographic focus is not formally defined. Zeneca is pseudonymous and has not disclosed a base of operations. His community and deal activity appear global, consistent with the distributed nature of NFT and Web3 ecosystems.
As an angel investor, Zeneca's influence comes primarily from audience reach and community trust rather than capital scale. His model – creator-first, investor-second – reflects a pattern common in Web3 where distribution and credibility are the scarce resources. Whether this translates into consistent investment returns at scale remains unclear, as no verified exit data or portfolio performance figures are public. His track record should be assessed with that transparency gap in mind.
